Tolazoline Hydrochloride White Raw Steroid Powders Adrenergic Blockers CAS 59-97-2

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Tolazoline Hydrochloride White Raw Steroid Powders Adrenergic Blockers CAS 59-97-2

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Tolazoline Hydrochloride White Raw Steroid Powders Adrenergic Blockers CAS 59-97-2

 

1. Description
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist. It is a vasodilator that is used to treat spasms of peripheral blood vessels (as in acrocyanosis). It has also been used (in conjunction with Sodium nitroprusside) successfully as an antidote to reverse the severe peripheral vasoconstriction which can occur as a result of overdose with certain 5-HT2A agonist drugs such as 25I-NBOMe,[citation needed]DOB and Bromodragonfly (prolonged severe vasoconstriction can lead to gangrene if untreated).

It is however most commonly used in veterinary medicine, to reverse xylazine-induced sedation.

Tolazoline hydrochloride Basic information
Product Name: Tolazoline hydrochloride
Synonyms: BENZIDAZOL HYDROCHLORIDE;BENZAZOLINE HYDROCHLORIDE;2-BENZYL-4,5-IMIDAZOLINE HCL;2-BENZYL-2-IMIDAZOLINE;2-BENZYL-2-IMIDAZOLINE HYDROCHLORIDE;2-BENZYL-2-IMINAZOLINE HYDROCHLORIDE;TIMTEC-BB SBB000360;PRISCOLINE HYDROCHLORIDE
CAS: 59-97-2
MF: C10H13ClN2
MW: 196.68
EINECS: 200-447-3
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Heterocycles;PRISCOLINE
Mol File: 59-97-2.mol
Tolazoline hydrochloride Chemical Properties
mp 172-176 °C
storage temp. -20°C Freezer, Under Inert Atmosphere
Sensitive Hygroscopic
Merck 14,9506
Stability: Hygroscopic
CAS DataBase Reference 59-97-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 22
RIDADR 2811
MSDS Information
Provider Language
ACROS English
ALFA English
Tolazoline hydrochloride Usage And Synthesis
Chemical Properties Pale Yellow Crystalline Solid
Usage a-adrenergic antagonist. A peripheral vasodilator
Usage Αn α-adrenergic antagonist. A peripheral vasodilator.
Usage adrenergic blocker

2. COA

Product name Tolazoline Hydrochloride MFG. Date 20130110
Package 1kg/bag Batch number FH-20130110
Testing Date 20130110 Exp Date 20150110
Standard USP32 Quantity 100kg
Cas No. 59-97-2 EINECS NO. 200-447-3
Molecular Formula C10H13ClN2 Molecular Weight 196.68
Function Main functions are as follows:
As short-acting receptor blocking drugs
Applications Main applications are as follows:
Medicine
Synonyms 2-Benzyl-2-imidazoline hydrochloride
Items Tested Specification Result
Characters White or off-white crystalline powder Confirms
Assay (HPLC) 99.0~101.0% Confirms
Density 1.09g/cm3 Confirms
Flash Point 158.3 Degree Confirms
Boiling Point 338.2Degree at 760mmHg Confirms
Melting point 172~176Degree Confirms
Conclusion Conforms USP32

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